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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10696 | CB2 modulator 1 | Cannabinoid Receptor | |
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia. | |||
T4583 | PFI-2 hydrochloride | (R)-PFI-2 hydrochloride,PFI-2 HCl | Histone Methyltransferase |
PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM), 500 fold active than (S)-PFI-2. | |||
T3033 | Deoxycorticosterone acetate | DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate | Glucocorticoid Receptor , Endogenous Metabolite , Adrenergic Receptor |
Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid. | |||
T1987 | PFI-2 | PFI2,PFI 2,(R)-PFI-2 | Histone Methyltransferase |
PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets. | |||
TQ0119 | Cirsimaritin | GABA Receptor | |
Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors. | |||
T3005 | 4-Hydroxychalcone | P-Cinnamoylphenol | Others , NF-κB |
4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice. | |||
T4904 | 1-Methylguanidine hydrochloride | Others , Endogenous Metabolite | |
Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibit... | |||
T21610 | Bradykinin (acetate) | Bradykinin Receptor | |
Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions. Enzy... | |||
T79516 | BT424 | Src | |
BT424, a specific HCK inhibitor, modulates macrophage activation and autophagy in vitro, and mitigates inflammation and renal fibrosis in the UUO model [1]. | |||
T38384 | Nexinhib20 | ||
Nexinhib20 is an inhibitor of the protein-protein interaction between the small GTPase Rab27a and its effector JFC1 (IC50 = 2.6 μM).[1] It inhibits myeloperoxidase (MPO) secretion induced by granulocyte macrophage colony... | |||
T61949 | Evogliptin | ||
Evogliptin (DA-1229) is a DPP4 inhibitor with oral activity. Evogliptin has significant and lasting hypoglycemic effect in mouse model. Evogliptin inhibits the production of the fibrosis and inflammatory in hepatocytes s... |